Identifying genetic susceptibility to Aspergillus fumigatus infection using collaborative cross mice and RNA-Seq approach.
Roa'a H S YosiefIqbal M LoneAharon NachshonHeinz HimmelbauerIrit Gat-ViksFuad A IraqiPublished in: Animal models and experimental medicine (2024)
Our findings emphasize the CC mouse model's power in fine mapping the genetic components underlying susceptibility towards Af. As a next step, eQTL analysis will be performed for our RNA-Seq data. Suggested candidate genes from our study will be further assessed with a human cohort with aspergillosis.