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T-Cell Lymphoblastic Lymphoma Arising in the Setting of Myeloid/Lymphoid Neoplasms with Eosinophilia: LMO2 Immunohistochemistry as a Potentially Useful Diagnostic Marker.

Magda ZanelliGiuseppe Gaetano LoscoccoElena SabattiniMaurizio ZizzoFrancesca SanguedolceLuigi PanicoDaniela FanniRaffaella SantiCecilia CapreraCristiana RossiAlessandra SorianoAlberto CavazzaAlessandro GiuntaCristina MecucciAlessandro M VannucchiStefano A PileriStefano Ascani
Published in: Cancers (2021)
LMO2 may represent a potentially useful marker to identify T-LBL developing in the context of M/LNs-Eo. In this setting, T-LBL shows LMO2 immunohistochemical profile overlapping with cortical thymocytes and iT-LBP, possibly reflecting different molecular patterns involved in the pathogenesis of T-LBL arising in the setting of M/LNs-Eo.
Keyphrases
  • diffuse large b cell lymphoma
  • dendritic cells
  • acute myeloid leukemia
  • rare case
  • single molecule