Inhibition of the mTOR Pathway Exerts Cardioprotective Effects Partly through Autophagy in CLP Rats.

Wen HanHao WangLongxiang Su Yun Long Na Cui Dawei Liu

Published in: Mediators of inflammation (2018)

Inhibition of the mTOR pathway has cardioprotective effects on myocardial dysfunction during sepsis induced by CLP, which is partly mediated through autophagy.

Keyphrases

oxidative stress
cell death
endoplasmic reticulum stress
signaling pathway
cell proliferation
intensive care unit
left ventricular
heart failure
septic shock