Antiprotozoal activity of auranofin on Trypanosoma cruzi, Leishmania tropica and Toxoplasma gondii: in vitro and ex vivo study.

Ahmet Yıldırım Ahmet Özbilgin Kor Yereli

Published in: Transactions of the Royal Society of Tropical Medicine and Hygiene (2023)

The detection antiprotozoal activity of auranofin on T. cruzi, L. tropica and T. gondii according to the IC50, CC50 and SI values is considered an important and promising development. This is significant because auranofin may be an effective alternative treatment for Chagas disease, leishmaniasis and toxoplasmosis in the future.

Keyphrases

toxoplasma gondii
trypanosoma cruzi
current status
room temperature
real time pcr
combination therapy
ionic liquid
quantum dots