Cumulative exposure to estrogen may increase the risk of migraine in women.
Nora Stensland BuggeKjersti Grøtta VetvikKarl Bjørnar AlstadhaugTonje BraatenPublished in: Cephalalgia : an international journal of headache (2024)
Older age at menarche appears to reduce migraine risk, whereas oral contraceptive use and having children appear to increase the risk. Further research is required to investigate the causality of these associations.