Initial responsiveness to darbepoetin alfa and its contributing factors in non-dialysis chronic kidney disease patients in Japan.

Terumasa HayashiHideki KatoKenichiro TanabeMasaomi NangakuHideki HirakataTakashi WadaHiroshi SatoYasushi YamazakiTakao MasakiTatsuo KagimuraHiroyasu YamamotoHiroki HaseMasahiro KamouchiEnyu ImaiKyoichi MizunoManabu IwasakiTadao AkizawaYoshiharu TsubakiharaShoichi MaruyamaIchiei Narita

Published in: Clinical and experimental nephrology (2020)

Non-responder to DA accounted for 13.3% of patients with non-dialysis CKD. Iron supplementation, low CRP, low NT-proBNP, and less proteinuria were predictive and modifiable factors associated with better initial response to DA.

Keyphrases

end stage renal disease
chronic kidney disease
peritoneal dialysis
ejection fraction
newly diagnosed
prognostic factors
replacement therapy
smoking cessation