MRI Automated T1 Signal Intensity Detection of Diffuse Brain Manganese Accumulation in Cirrhosis.

Ke WeiThao T TranPatrick W ChangAnnie MalekieKaren ChuLea AlhilaliMatthew T BorzageEdward MenaMichael G HarringtonKevin S King

Published in: Journal of neuroimaging : official journal of the American Society of Neuroimaging (2020)

Automatic assessment of T1 SI allows for rapid, objective identification of widespread T1 shortening associated with manganese deposition in cirrhosis, consistent with the global deposition of neurotoxic manganese seen in pathology studies. This automated T1 assessment may have broader utility for other conditions beyond cirrhosis impacting T1 SI.

Keyphrases

deep learning
machine learning
loop mediated isothermal amplification
high throughput
magnetic resonance imaging
room temperature
contrast enhanced
white matter
low grade
magnetic resonance
computed tomography
brain injury
sensitive detection
high grade
ionic liquid
quantum dots