RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation.
Katarzyna SzołtysekPatryk JanusGracjana ZającTomasz StokowyAnna WalaszczykWiesława WidłakBartosz WojtaśBartłomiej GielniewskiSimon CockellNeil D PerkinsMarek KimmelPiotr WidlakPublished in: BMC genomics (2018)
Four new candidates for genes directly co-regulated by NF-κB and p53 were revealed.
Keyphrases
- signaling pathway
- induced apoptosis
- genome wide identification
- lps induced
- transcription factor
- genome wide
- pi k akt
- cell cycle arrest
- oxidative stress
- nuclear factor
- single cell
- inflammatory response
- dna methylation
- genome wide analysis
- cell death
- endoplasmic reticulum stress
- cell proliferation
- immune response
- gene expression
- toll like receptor