Local anesthetics elicit immune-dependent anticancer effects.
Lucillia BezuAlejandra Wu ChuangAllan SauvatJuliette HumeauWei XieGiulia CerratoPeng LiuLiwei ZhaoShuai ZhangJulie Le NaourJonathan G PolPeter van EndertOliver KeppFabrice BarlesiGuido KroemerPublished in: Journal for immunotherapy of cancer (2022)
Altogether, these results indicate that local anesthetics induce a therapeutically relevant pattern of immunogenic stress responses in cancer cells.
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