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Peripheral blood mononuclear cells extracts VEGF protein levels and VEGF mRNA: Associations with inflammatory molecules in a healthy population.

Vesna GorenjakDwaine R VanceAlexandros M PetrelisMaria G StathopoulouSébastien DadéSaid El ShamiehHelena MurrayChristine MassonJohn LamontPeter FitzgeraldSophie Siest
Published in: PloS one (2019)
These findings provide novel insights that may assist in the development of new tissue and mRNA isoform specific measurements of VEGF levels, which may positively contribute to predicting the risk of common complex diseases and response of currently used anti-VEGF agents, and developing of novel targeted therapies for VEGF-related pathophysiology.
Keyphrases
  • vascular endothelial growth factor
  • endothelial cells
  • oxidative stress
  • small molecule
  • protein protein