Urban-Rural Differences in Schizophrenia Risk: Multilevel Survival Analyses of Individual- and Neighborhood-Level Indicators, Urbanicity and Population Density in a Danish National Cohort Study.
Carsten Bøcker PedersenSussie AntonsenAllan TimmermannMarianne Giørtz PedersenLinda EjlskovHenriette Thisted HorsdalEsben AgerboRoger T WebbOle Raaschou-NielsenTorben SigsgaardClive E SabelChun Chieh FanWesley K ThompsonPublished in: Schizophrenia bulletin open (2021)
In the largest prospective multilevel survival analyses of schizophrenia risk conducted to date, multiple neighborhood-level characteristics were associated with raised schizophrenia risk, with these contextual factors explaining most of the elevated risk linked with urbanicity. However, the unexplained heterogeneity that was evident in our multilevel models indicates that our understanding of the role of urbanicity in schizophrenia's etiology remains incomplete.