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Metabolic syndrome and its pharmacologic treatment are associated with the time to castration-resistant prostate cancer.

Jiun-Hung GengAnna PlymKathryn L PenneyMark PomerantzLorelei A MucciAdam S Kibel
Published in: Prostate cancer and prostatic diseases (2022)
Our study suggests that metabolic syndrome is a risk factor for earlier progression from castration-sensitive to castration-resistant prostate cancer and raises the possibility that treatment, such as statin use, may slow the time to progression.
Keyphrases
  • metabolic syndrome
  • cardiovascular disease
  • insulin resistance
  • coronary artery disease
  • type diabetes
  • cardiovascular risk factors
  • skeletal muscle
  • replacement therapy