Biomarkers of histologic severity in children with severe or atypical acute post-streptococcal glomerulonephritis.

Severe APSGN is associated with a pronounced reduction in eGFR. Calculation of eGFR in this small group of patients may assist in identifying which patient should have an urgent kidney biopsy to facilitate a more accurate clinical diagnosis and management plan. A higher resolution version of the Graphical abstract is available as Supplementary information.