Human brain tissue identification using coherent anti-Stokes Raman scattering spectroscopy and diffuse reflectance spectroscopy for deep brain stimulation surgery.
Sébastien JerczynskiMireille QuémenerValérie Pineau NoëlAntoine RousseauElahe ParhamAlexandre BédardShadi MasoumiThomas CharlandAnthony DrouinJonathan RousselValérie DionneThomas ShoonerAnaïs ParrotMohamad A TakechÉric PhilippeDamon T DePaoliLéo CantinMartin ParentDaniel C CôtéPublished in: Neurophotonics (2024)
It is possible to use optical measurements from the DBS lead during surgery to identify WM and GM and possibly the presence of blood in human brain tissue. The proposed optical tool could inform the surgeon during the lead placement if the lead has reached the target as planned. Our tool could eventually replace microelectrode recordings, which would streamline the process and reduce surgery time. Further developments are required to fully integrate these tools into standard clinical procedures.
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