Predictors of first-line antiretroviral therapy failure among adults and adolescents living with HIV/AIDS in a large prevention and treatment program in Nigeria.

Nicaise NdembiFati Murtala-IbrahimMonday TolaJibreel JumareAhmad AliyuPeter AlabiCharles MensahAlash'le AbimikuMiguel E Quiñones-MateuTrevor A CrowellSoo-Yon RheeRobert W ShaferRavindra GuptaWilliam BlattnerManhattan E CharuratPatrick Dakum

Published in: AIDS research and therapy (2020)

In this cohort of Nigerian PLWH followed for a period of 9 years, immunologic criteria poorly predicted virologic failure. Furthermore, a subset of samples showed that patients failing ART for extended periods of time had HIV-1 strains harboring drug resistance mutations.

Keyphrases

antiretroviral therapy
hiv infected
hiv positive
human immunodeficiency virus
hiv infected patients
hiv aids
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
physical activity
hepatitis c virus
patient reported outcomes
peritoneal dialysis
combination therapy
smoking cessation