Immunohistochemical staining of leptin is associated with grade, stage, lymph node involvement, recurrence, and hormone receptor phenotypes in breast cancer.
Mohamad Nidal KhabazAmer AbdelrahmanNadeem ButtLila DamnhoryMohamed ElshalAlia M AldahlawiSwsan AshoorBasim Al-MaghrabiPauline DobsonBarry BrownKaltoom Al-SakkafMohmmad Al-QahtaniMohamad Nidal KhabazPublished in: BMC women's health (2017)
Our preliminary findings support leptin clinical value in confirming BC diagnosis as well as prognosis. These results suggest that leptin molecule is an important biomarker that could identify type, grade, stage, lymph node involvement, relapse and prognosis in breast cancer.