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Anticoagulated patients exhibit intact endogenous thrombin potential using ST Genesia unlike the Calibrated Automated Thrombogram.

Tuukka Antero HelinMarja LemponenRiitta LassilaLotta Joutsi-Korhonen
Published in: Research and practice in thrombosis and haemostasis (2021)
The ST Genesia data did not correlate with CAT, but it was independently associated with INR, anti-Xa, and DOAC concentrations. The lag time and peak responses were similar; the major differences were that ST Genesia showed no ETP effect of DOACs and failed to give readout at high INR or anti-Xa activity.
Keyphrases
  • end stage renal disease
  • direct oral anticoagulants
  • machine learning
  • deep learning
  • high throughput
  • big data
  • atrial fibrillation
  • venous thromboembolism
  • single cell