Up-Regulation of miR-9-5p Inhibits Hypoxia-Ischemia Brain Damage Through the DDIT4-Mediated Autophagy Pathways in Neonatal Mice.

Chengcheng GaiXiaohui XingYan SongYijing ZhaoZige JiangYahong ChengYilei XiaoZhen Wang

Published in: Drug design, development and therapy (2023)

The study indicates that miR-9-5p-mediated HI injury is regulated by DDIT4-mediated autophagy pathway and up-regulation of miR-9-5p level may provide a potential therapeutic effect on HI brain damage.

Keyphrases

oxidative stress
cell death
resting state
endoplasmic reticulum stress
white matter
signaling pathway
type diabetes
endothelial cells
metabolic syndrome
climate change
functional connectivity
adipose tissue
cerebral ischemia
risk assessment
wild type