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Antibiotic resistance genes are differentially mobilized according to resistance mechanism.

Tue Kjærgaard NielsenPatrick Denis BrowneLars Hestbjerg Hansen
Published in: GigaScience (2022)
In this study, ARGs in all complete bacterial genomes are classified by their association with MGEs, using the proposed ARG-MOB scale. These results have consequences for the design and interpretation of studies screening for resistance determinants, as mobilized ARGs pose a more concrete risk to human health. An interactive table of all results is provided for future studies targeting highly mobilized ARGs.
Keyphrases
  • antibiotic resistance genes
  • human health
  • peripheral blood
  • wastewater treatment
  • microbial community
  • risk assessment
  • anaerobic digestion
  • case control
  • climate change
  • current status
  • cancer therapy