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G Protein-Coupled Estrogen Receptor 1 (GPER1) Mediates Aldosterone-Induced Endothelial Inflammation in a Mineralocorticoid Receptor-Independent Manner.

Ziwei TangQi Fu LiQingfeng ChengMei MeiYing SongZhipeng DuWenwen HeJinbo HuShumin YangZhihong Wang
Published in: International journal of endocrinology (2021)
These findings not only demonstrated the role of GPER1 in aldosterone-induced vascular inflammation but also suggested an alternative for pharmaceutical treatment of hyperaldosteronism considering the unsatisfying effect on cardiovascular risks with MR antagonists.
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