Development of a Flow Photochemical Aerobic Oxidation of Benzylic C-H Bonds.

Mathieu LesieurChristophe GenicotPatrick Pasau

Published in: Organic letters (2018)

A continuous mesofluidic process has been developed for benzylic C-H oxidation with moderate to good yields using a photocatalyst (riboflavin tetraacetate, RFT) activated by a UV lamp and an iron additive [Fe(ClO4)2] via incorporation of singlet oxygen (1O2) for the direct formation of oxidized C═O or CH-OH compounds.

Keyphrases

visible light
high intensity
hydrogen peroxide
room temperature
electron transfer
loop mediated isothermal amplification
low density lipoprotein
energy transfer
ionic liquid