Systolic anterior motion of the anterior mitral valve leaflet begins in subclinical hypertrophic cardiomyopathy.

Samuel SeitlerSurani De Zoysa AnthonyChinwe C C ObianyoPetros SyrrisVimal PatelDaniel M SadoViviana MaestriniSilvia CastellettiStephen WalshBenjamin O'BrienJames C MoonGabriella Captur

Published in: European heart journal. Cardiovascular Imaging (2023)

Dyskinesia of the aorto-mitral apparatus, including SAM of the elongated AMVL, is detectable in subclinical HCM, before the development of LVH or LA enlargement. These data have the potential to improve our understanding of early phenotype development and LVOTO-predisposition in HCM.

Keyphrases

hypertrophic cardiomyopathy
mitral valve
left ventricular
left atrial
heart failure
aortic stenosis
blood pressure
risk assessment
mass spectrometry
human health
aortic valve
coronary artery disease
high speed