Login / Signup

Hypofucosylation of Unc5b regulated by Fut8 enhances macrophage emigration and prevents atherosclerosis.

Xi YangLimei MaJun ZhangLinmu ChenZhen ZouDi ShenHui HeLei ZhangJun ChenZhiyi YuanXia QinChao Yu
Published in: Cell & bioscience (2023)
These results demonstrated that hypofucosylation of Unc5b regulated by Fut8 is positively associated with the delay of the atherosclerotic process by promoting the migration of foamy macrophages. These findings identify a promising therapeutic target for atherosclerosis.
Keyphrases
  • cardiovascular disease
  • adipose tissue
  • mouse model
  • type diabetes