A single Bayesian estimator for iohexol clearance estimation in ICU, liver failure and renal transplant patients.

Alexandre DestereCharlotte Salmon GandonnièreAnders AsbergVéronique Loustaud-RattiPaul CarrierStephan EhrmannChantal Barin-Le GuellecPierre MarquetJean Baptiste Woillard

Published in: British journal of clinical pharmacology (2022)

A single MAP-BE of iohexol based on a three-sample LSS for four heterogeneous populations was developed and allowed accurate estimation of GFR in kidney transplant patients, slightly biased in stable ICU patients and slightly imprecise in unstable ICU patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
liver failure
patient reported outcomes
mass spectrometry
mechanical ventilation
patient reported
acute respiratory distress syndrome