Taurine Metabolism Aggravates the Progression of Lupus by Promoting the Function of Plasmacytoid Dendritic Cells.

Nan ShenHuihua DingYao MengGuanhua LiQiong FuQiang GuoZhihua YinZhizhong YeHaibo ZhouNan Shen

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2020)

Taurine metabolism is involved in the development of SLE by enhancing pDC-mediated type I IFN production. Targeted inhibition of taurine or implementation of a taurine-restricted diet has therapeutic potential in SLE.

Keyphrases

dendritic cells
systemic lupus erythematosus
disease activity
immune response
regulatory t cells
healthcare
primary care
rheumatoid arthritis
physical activity
weight loss
drug delivery