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The E3 Ubiquitin Ligase Peli1 Deficiency Promotes Atherosclerosis Progression.

Fabienne BurgerDaniela BaptistaAline RothKarim J BrandtKapka Miteva
Published in: Cells (2022)
In the present study, we uncover a crucial role for Peli1 in atherosclerosis as an important regulator of inflammation and VSMCs phenotypic modulation and subsequently atherosclerotic plaque destabilization.
Keyphrases
  • cardiovascular disease
  • oxidative stress
  • coronary artery disease
  • transcription factor
  • type diabetes
  • vascular smooth muscle cells
  • replacement therapy