Sex-specific trajectories of insulin resistance markers and reduced renal function during 18 years of follow-up; TLGS.

Atieh Amouzegar Mohammadjavad HonarvarSafdar MasoumiMaryam TohidiLadan MehranFereidoun Azizi

Published in: The Journal of clinical endocrinology and metabolism (2022)

An increasing trend of HOMA-IR is associated with a higher risk of CKD in men and women. Among clinical insulin resistance surrogate markers, abnormal trajectory patterns of LAP in women and TyG and VAI in both sexes are associated with a higher risk of CKD.

Keyphrases

insulin resistance
polycystic ovary syndrome
chronic kidney disease
adipose tissue
high fat diet
metabolic syndrome
skeletal muscle
type diabetes
high fat diet induced
depressive symptoms
pregnant women