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Acute administration of beta-caryophyllene prevents endocannabinoid system activation during transient common carotid artery occlusion and reperfusion.

Laura PoddigheGianfranca CartaMaria Pina SerraTiziana MelisMarianna BoiSara LisaiElisabetta MurruLaura MureddaMaria ColluSebastiano BanniMarina Quartu
Published in: Lipids in health and disease (2018)
Collectively, the pre-treatment with BCP, likely acting as agonist for CB2 and PPAR-alpha receptors, modulates in a beneficial way the ECS activation and the lipoperoxidation, taken as indicative of oxidative stress. Furthermore, our results support the evidence that BCP may be used as a dietary supplement to control the physiological response to the hypoperfusion/reperfusion-induced oxidative stress.
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