Atherosclerosis quantification and cardiovascular risk: the ISCHEMIA trial.
Nick S NurmohamedJames K MinRebecca AnthopolosHarmony R ReynoldsJames P EarlsTami CrabtreeG B John ManciniJonathon LeipsicMatthew J BudoffCameron J HagueSean M O'BrienGregg W StoneJeffrey S BergerRobert DonninoMandeep S SidhuJonathan D NewmanWilliam E BodenBernard R ChaitmanPeter H StoneSripal BangaloreJohn A SpertusDaniel B MarkLeslee J ShawJudith S HochmanDavid J MaronPublished in: European heart journal (2024)
In ISCHEMIA, total plaque volume was associated with cardiovascular death or myocardial infarction. In this highly diseased, high-risk population, enhanced assessment of atherosclerotic burden using AI-QCT-derived measures of plaque volume and composition modestly improved event prediction.