Pre-XDR congenital tuberculosis in an extremely premature baby.

Alison BoastJeu Ann HowCharis LauArun SettDamian GilbyAndrew BurkeBrett McWhinneyConnor WrightAdrian TramontanaMaria GlobanJustin DenholmStephen M GrahamJoshua Osowicki

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2023)

We describe a case of congenital tuberculosis in an extremely premature baby, with rapid molecular detection of a pre-XDR pattern of drug resistance. The baby was treated successfully with a regimen including bedaquline and delamanid, drugs not previously described in the treatment of congenital TB.

Keyphrases

mycobacterium tuberculosis
drug resistant
hiv aids
emergency department
multidrug resistant
adverse drug
hepatitis c virus
hiv infected
drug induced
sensitive detection
smoking cessation