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Ancestry of cells must be considered in bioengineering.

Erika M MooreJosephine B AllenConnie J MulliganElizabeth C Wayne
Published in: Nature reviews. Materials (2021)
Bioengineered platforms, intended to be used in the investigation of human health and disease, often incorporate cells of unknown ancestry or that lack diversity. To develop tools and platforms that benefit the entire human population, we must consider the ancestry of cells and intentionally diversify the cells we use in our designs.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • human health
  • risk assessment
  • endothelial cells
  • endoplasmic reticulum stress
  • oxidative stress
  • climate change