Folic acid and methotrexate use and their association with COVID-19 diagnosis and mortality: a case-control analysis from the UK Biobank.

Ruth ToplessRalph GreenSarah L MorganPhilip C RobinsonTony MerrimanAngelo Lino Gaffo

Published in: BMJ open (2022)

We report an association of increased risk for COVID-19 diagnosis and COVID-19-related death in people prescribed folic acid supplementation. Our results also suggest that methotrexate might attenuate these associations.

Keyphrases

type diabetes
coronavirus disease
sars cov
case control
high dose
respiratory syndrome coronavirus
low dose
drug induced