Login / Signup

Data usefulness in determining cause of stillbirth in South Asia.

Robert L GoldenbergKay HwangSarah SaleemShiyam Sunder TikmaniS YogeshkumarVardendra KulkaniNajia GhanchiSheetal HarakuniImran AhmedZeeshan UddinShivaprasad S GoudarGowder GuruprasadSangappa DhadedNorman GocoRobert M SilverElizabeth M McClure
Published in: BJOG : an international journal of obstetrics and gynaecology (2023)
Based on this analysis, maternal clinical history, placental histology and fetal examination were most informative. Comparing the placental and fetal weights with recognised standards was useful in nearly half the cases. Fetal tissue histology and PCR were also informative. Of all the potential tests of MITS-obtained specimens, we would first recommend histological evaluation of the lungs, and using a multiplex PCR platform would determine pathogens in blood and brain/CSF. We recognise that this approach will not identify some causes, including some genetic and internal organ anomalies, but will confirm most common causes of stillbirth and most of the preventable causes of stillbirth in low- and middle-income countries.
Keyphrases