Clinical Evidence of the Relationship Between Alanine Aminotransferase and Diabetic Kidney Disease.
Yaru BiYang YangXiaojie YuanJiping WangZhiyuan LiuSuyan TianChenglin SunPublished in: Diabetes, metabolic syndrome and obesity : targets and therapy (2024)
-shaped nonlinear association between ALT and DKD was found in our clinical data and NHANES data. DKD risk was increased by both lower or higher ALT activity. To confirm the causality of nonlinear relationship, larger prospective studies or Mendelian randomization analysis are required.