Endotoxemia and circulating bacteriome in severe COVID-19 patients.
Phatadon SirivongrangsonWin KulvichitSunchai PayungpornTrairak PisitkunAriya ChindampornSadudee PeerapornratanaPrapaporn PisitkunSuwalak ChitcharoenVorthon SawaswongNavaporn WorasilchaiSarinya KampunyaOpass PutcharoenThammasak ThawitsriNophol LeelayuwatanakulNapplika KongpolpromVorakamol PhoophiboonThitiwat SriprasartRujipat SamransamruajkitSomkanya TungsangaKanitha TiankanonNuttha LumlertgulAsada LeelahavanichkulTueboon SriphojanartTerapong TantawichienUsa ThisyakornChintana ChirathawornKearkiat PraditpornsilpaKriang TungsangaSomchai Eiam-OngVisith SitprijaJohn A KellumNattachai SrisawatPublished in: Intensive care medicine experimental (2020)
Bacterial DNA and toxins were discovered in virtually all severely ill COVID-19 pneumonia patients. This raises a previously unrecognized concern for significant contribution of bacterial products in the pathogenesis of this disease.