Rebalancing glucolipid metabolism and gut microbiome dysbiosis by nitrate-dependent alleviation of high-fat diet-induced obesity.

Linsha MaLiang HuLuyuan JinJiangyi WangXiangchun LiWeili WangShimin ChangChunmei ZhangJingsong WangSonglin Wang

Published in: BMJ open diabetes research & care (2021)

Inorganic dietary nitrate alleviated HFD-induced obesity and ameliorated disrupted glucolipid metabolism via NO3 --NO2 --NO pathway activation and gut microbiome modulation.

Keyphrases

high fat diet induced
insulin resistance
high fat diet
nitric oxide
drinking water
metabolic syndrome
adipose tissue
skeletal muscle
type diabetes
high glucose
weight loss
diabetic rats
weight gain
endothelial cells
oxidative stress
resting state