Prediction of locally advanced rectal cancer response to neoadjuvant chemoradiation therapy using volumetric multiparametric MRI-based radiomics.
Maria El HomsiOctavia BaneValentin FauveauStefanie HectorsNaik Vietti VioliPatricia SyllaHuai-Bin KoJordan CuevasGuillermo CarbonellAnthony NehlsenRami VanguriSatish ViswanathSachin JambawalikarHiram ShaishBachir TaouliPublished in: Abdominal radiology (New York) (2023)
Radiomic models obtained from pre-treatment MRI show good to excellent performance for the prediction of pCR in patients with LARC, superior to clinical parameters and CEA. A larger study is needed for confirmation of these results.
Keyphrases
- rectal cancer
- locally advanced
- contrast enhanced
- neoadjuvant chemotherapy
- magnetic resonance imaging
- phase ii study
- squamous cell carcinoma
- radiation therapy
- diffusion weighted imaging
- magnetic resonance
- lymph node metastasis
- computed tomography
- stem cells
- lymph node
- clinical trial
- mesenchymal stem cells
- study protocol
- real time pcr