Medium and large alleles of the PGC gene are risk factors for gastric cancer.
Josefina Yoaly Sánchez-LópezKatia Carolina Vázquez-IbarraAndrea Marlene García-MuroAzaria García-RuvalcabaSergio Pacheco-SoteloLuis Carlos Díaz-HerreraMarıa Eugenia Marin-ContrerasPublished in: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine (2023)
Previous studies have related PGC short alleles to risk for or protection against GC depending on the ethnic origin of the population. In our study, medium alleles were related to risk for GC. Further studies are required to establish the importance of this polymorphism in the origin of gastric neoplasia.