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Are serum brain-derived neurotrophic factor concentrations related to brain structure and psychopathology in late childhood and early adolescence?

Celia Maria de AraujoWalter SwardfagerAndre ZugmanHugo Cogo-MoreiraSintia I BelangeroVanessa K OtaLeticia M SpindolaHakon HakonarsonRenata PellegrinoAry GadelhaGiovanni A SalumPedro M PanRodrigo B MansurMarcelo HoexterFelipe PiconJoão R SatoElisa BrietzkeRodrigo Grassi-OliveiraLuis A P RohdeEuripedes C MiguelRodrigo A BressanAndrea P Jackowski
Published in: CNS spectrums (2019)
No evidence was found to support serum BDNF concentrations as a useful marker of developmental differences in brain and behavior in early life. Negative findings were replicated in 2 of the largest independent samples investigated to date.
Keyphrases
  • early life
  • resting state
  • white matter
  • functional connectivity
  • depressive symptoms
  • cerebral ischemia
  • multiple sclerosis
  • stress induced
  • mass spectrometry
  • blood brain barrier