The diagnostic and prognostic value of red cell distribution width in cardiovascular disease; current status and prospective.
Seyed Mostafa ParizadehReza Jafarzadeh-EsfehaniAmirhossein BahreyniMaryam GhandehariMojtaba ShafieeFarzad RahmaniMohammar R ParizadehSima SeifiMajid Ghayour MobarhanGordon A FernsSoodabeh ShahidsalesSeyed Mahdi HassanianPublished in: BioFactors (Oxford, England) (2019)
The red blood cell distribution width (RDW) is an index of the heterogeneity of circulating red blood cell size, which along with other standard complete blood count (CBC) parameters are used to identify hematological system diseases. Besides hematological disorders, several clinical studies have shown that an increased in the RDW may be associated with other diseases including acute pancreatitis, chronic kidney disease, gastrointestinal disorders, cancer, and of special interest in this review, cardiovascular disease (CVD). The diagnostic and prognostic value of RDW in different CVD (acute coronary syndrome, ischemic cerebrovascular disease, peripheral artery disease, atrial fibrillation, heart failure, and acute ischemic stroke) has been reviewed in this article, to provide an understanding how its measurement may be applied to improve the management of these conditions.
Keyphrases
- red blood cell
- cardiovascular disease
- acute ischemic stroke
- peripheral artery disease
- heart failure
- acute coronary syndrome
- chronic kidney disease
- atrial fibrillation
- current status
- single cell
- percutaneous coronary intervention
- papillary thyroid
- end stage renal disease
- type diabetes
- cardiovascular events
- cardiovascular risk factors
- cell therapy
- squamous cell
- stem cells
- oxidative stress
- antiplatelet therapy
- squamous cell carcinoma
- childhood cancer
- venous thromboembolism
- coronary artery disease
- bone marrow