Ubiquitin-specific peptide 22 acts as an oncogene in gastric cancer in a son of sevenless 1-dependent manner.
ChitChoon LimJia-Cheng XuTian-Yin ChenJia-Xin XuWei-Feng ChenJian-Wei HuQuan-Lin LiYi-Qun ZhangPublished in: Cancer cell international (2020)
Our results suggest that USP22 acts as an oncogene in gastric cancer in a SOS1-dependent manner, identifying the USP22/SOS1/RAS axis as a potential therapeutic target in gastric cancer.