Investigation of Cerebral O-(2-[18F]Fluoroethyl)-L-Tyrosine Uptake in Rat Epilepsy Models.
Carina StegmayrRainer SurgesChang-Hoon ChoiNicole BurdaGabriele StoffelsChristian FilßAntje WilluweitBernd NeumaierAlexander HeinzelN Jon ShahFelix M MottaghyKarl-Josef LangenPublished in: Molecular imaging and biology (2021)
There was no evidence for increased cerebral [18F]FET uptake after epileptic seizures neither in the rat models nor in patients. The SE model even showed decreased [18F]FET uptake throughout the brain. We conclude that epileptic seizures per se do not cause a longer lasting increased [18F]FET accumulation and are unlikely to be a major cause of pitfall for brain tumor diagnostics.