Immunomodulatory and anti-inflammatory effects of Phellinus linteus mycelium.

Mi-Rae ShinJi Hye LeeJin A LeeMin Ju KimHae-Jin ParkByeong Wook ParkSeung Bo SeoSeong-Soo Roh

Published in: BMC complementary medicine and therapies (2021)

Taken together, these results showed an immunomodulatory effect of PLM about an elevated INF-γ/IL4 ratio, as an index of Th1/Th2, as well as the anti-inflammatory effect in the LPS-stimulated RAW264.7 cells. Therefore, our findings demonstrate that PLM possesses immunostimulatory and anti-inflammatory effects.

Keyphrases

anti inflammatory
induced apoptosis
cell cycle arrest
inflammatory response
endoplasmic reticulum stress
cell death
oxidative stress