Features of patients who developed hepatocellular carcinoma after direct-acting antiviral treatment for hepatitis C Virus.
Seiichi MawatariKotaro KumagaiKohei OdaKazuaki TabuSho IjuinKunio FujisakiShuzo TashimaYukiko InadaHirofumi UtoAkiko SaisyojiYasunari HiramineMasafumi HashiguchiTsutomu TamaiTakeshi HoriOhki TaniyamaAi ToyodomeHaruka SakaeTakeshi KureKazuhiro SakuraiAkihiro MoriuchiShuji KanmuraAkio IdoPublished in: PloS one (2022)
EOT-AFP ≥5.3 ng/mL is useful for predicting HCC development after an SVR. However, AFP does not increase in patients with EOT-AFP <5.3 ng/mL at the onset of HCC. The combination of EOT-AFP, age, sex, HA, and EOT-Alb is important for predicting carcinogenesis.