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Combining donor derived cell free DNA and gene expression profiling for non-invasive surveillance after heart transplantation.

Erik J HenricksenYasbanoo MoayediSaira PurewalJulien Valverde TwiggsKian WaddellHelen LuikartJiho HanKent Y FengBrian WaydaRoy LeeYasuhiro ShudoShirin JimenezKiran K KhushJeffrey J Teuteberg
Published in: Clinical transplantation (2022)
Compared to post-transplant rejection surveillance with GEP alone, pairing dd-cfDNA and GEP testing was associated with similar survival and rejection-free survival at 1 year while requiring significantly fewer biopsies.
Keyphrases
  • free survival
  • gene expression
  • public health
  • dna methylation
  • single cell