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Urine complement proteins are associated with kidney disease progression of type 2 diabetes in Korean and American cohorts.

Donghwan YunSohyun BaeYuqian GaoLauren LopezDo Hyun HanCarrie D NicoraTae Youn KimKyung Chul MoonDong-Ki KimThomas L FillmoreYon Su KimAvi Z RosenbergWeijie WangPinaki SarderWei-Jun QianMaryam AfkarianSeung Seok Han
Published in: medRxiv : the preprint server for health sciences (2024)
Urinary proteomic profiling confirms the association between the complement pathway and rapid DKD progression in two independent cohorts. These results suggest a need to further investigate complement pathway inhibition as a novel treatment for DKD.
Keyphrases
  • type diabetes
  • glycemic control
  • insulin resistance
  • quantum dots
  • smoking cessation