Neurostructural Differences in Adolescents With Treatment-Resistant Depression and Treatment Effects of Transcranial Magnetic Stimulation.

Bhedita Jaya Seewoo Jennifer RodgerMark A DemitrackKaren L HeartJohn D PortJeffrey R StrawnPaul E Croarkin

Published in: The international journal of neuropsychopharmacology (2022)

Amygdala volumes were reduced in this sample of adolescents with MDD and TRD. TMS may normalize this volumetric finding, raising the possibility that TMS has neurostructural frontolimbic effects in adolescents with TRD. TMS also appears to have positive effects proximal to the site of stimulation.

Keyphrases

transcranial magnetic stimulation
high frequency
young adults
physical activity
functional connectivity
depressive symptoms
sleep quality