Effects of cyclophosphamide administration on ovarian dysfunction in pediatric patients with connective tissue diseases: A systematic scoping review.
Ken-Ei SadaTakako MiyamaeKayoko KanekoSakiko IsojimaKunihiro IchinoseMasakazu MatsushitaKenji OkuYasunori IwataKeishi FujioAtsuko MurashimaYoshiya TanakaAyako NakajimaPublished in: Modern rheumatology (2024)
This review suggested that CY use in childhood may not conclusively have clinically significant effects on ovarian function. Further investigation needed on CY's effect on hormonal levels, fertility, and pregnancy outcomes.