Phase-Resolved Functional Lung (PREFUL) MRI to Quantify Ventilation: Feasibility and Physiological Relevance in Severe Asthma.

Yonni FriedlanderSamal MunidasaAshutosh ThakarNandhitha RagunayakamCarmen VenegasMelanie KjarsgaardBrandon ZanetteDante P I CapaldiGiles SantyrParameswaran NairSarah Svenningsen

Published in: Academic radiology (2024)

PREFUL-derived VDP is responsive to bronchodilator therapy in asthma and is associated with measures of airflow obstruction and small airway dysfunction. These findings validate PREFUL VDP as a physiologically relevant and accessible ventilation imaging outcome measure in asthma.

Keyphrases

chronic obstructive pulmonary disease
lung function
respiratory failure
allergic rhinitis

mechanical ventilation
high resolution
magnetic resonance imaging
contrast enhanced

oxidative stress
cancer therapy
cystic fibrosis
intensive care unit

mesenchymal stem cells
acute respiratory distress syndrome
bone marrow
replacement therapy