Phase-Resolved Functional Lung (PREFUL) MRI to Quantify Ventilation: Feasibility and Physiological Relevance in Severe Asthma.
Yonni FriedlanderSamal MunidasaAshutosh ThakarNandhitha RagunayakamCarmen VenegasMelanie KjarsgaardBrandon ZanetteDante P I CapaldiGiles SantyrParameswaran NairSarah SvenningsenPublished in: Academic radiology (2024)
PREFUL-derived VDP is responsive to bronchodilator therapy in asthma and is associated with measures of airflow obstruction and small airway dysfunction. These findings validate PREFUL VDP as a physiologically relevant and accessible ventilation imaging outcome measure in asthma.
Keyphrases
- chronic obstructive pulmonary disease
- lung function
- respiratory failure
- allergic rhinitis
- mechanical ventilation
- high resolution
- magnetic resonance imaging
- contrast enhanced
- oxidative stress
- cancer therapy
- cystic fibrosis
- intensive care unit
- mesenchymal stem cells
- acute respiratory distress syndrome
- bone marrow
- replacement therapy