Early life overnutrition impairs plasticity of non-neuronal brainstem cells and drives obesity in offspring across development in rats.

Claudia G LiberiniMisgana GhidewonTyler LingRinzin LhamoNina JunterealLauren M SteinMatthew R Hayes

Published in: International journal of obesity (2005) (2020)

Current findings are very provocative, considering the importance of the DVC in appetite regulation, suggesting that HFSD-consumption during early life may contribute to subsequent obesity risk via DVC cytoarchitectural changes.

Keyphrases

early life
weight loss
insulin resistance
metabolic syndrome
induced apoptosis
high fat diet induced
type diabetes
weight gain
high fat diet
cell cycle arrest
endoplasmic reticulum stress
cell death
signaling pathway
subarachnoid hemorrhage
pi k akt